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Nanomedicine for improved efficacy of tuberculosis drugs – Pharmacokinetic importance

Author: Hayeshi, R Date: Oct 2012 This presentation focuses on the importance of pharmacokinetics in nanomedicine. Read more
Qualitative and quantitative intravaginal targeting: Key to anti-HIV-1 microbicide delivery from test tube to in vivo success

Author: Pillay, V ; Mashingaidze, F ; Choonara, YE ; Du Toit, LC ; Buckmann, E ; Maharaj, V ; Ndesendo, VMK ; Kumar, P Date: Jun 2012 The past decade has seen several effective anti-HIV-1 agent discoveries, yet microbicides continue to disappoint clinically. Our review expounds the view that unsatisfactory microbicide failures may be a result of inefficient delivery systems ... Read more
Summary reports for key Hoodia clinical studies

Author: Maharaj, VJ Date: Dec 2011 The CSIR has acquired the reports to 14 clinical studies in which Hoodia has been assesses, using crude extracts and concentrated active ingredients formulated in a number of different ways. In many of the studies Hoodia was found to be ... Read more
UCT943, a next-generation plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of Malaria

Author: Brunschwig, C ; Lawrence, N ; Taylor, D ; Abay, E ; Njoroge, M ; Basarab, GS ; Le Manach, C ; Paquet, T ; Cabrera, DG ; Mancama, Dalubuhle T Date: Sep 2018 The 2-aminopyridine MMV048 was the first drug candidate inhibiting Plasmodium phosphatidylinositol 4-kinase (PI4K), a novel drug target for malaria, to enter clinical development. In an effort to identify the next generation of PI4K inhibitors, ... Read more

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Browsing by Subject "Pharmacokinetics"

Browsing by Subject "Pharmacokinetics"

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