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Preliminary formulation and characterization of solid lipid nanoparticles containing chloroquine and a P-glycoprotein inhibitor: Influences of lipid-surfactant ratios

Author: Nzekwe, IT ; Azodo, VI ; Agubata, CO ; Naicker, B ; Okore, V ; Esimone, CO Date: Feb 2015 Chloroquine, a once useful therapy, currently faces problems of plasmodial resistance mediated through a number of mechanisms, such as P-glycoprotein (P-gp) mediated drug efflux, which makes attainment of adequate drug levels impossible. In ... Read more

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Browsing by Subject "P-gp"

Browsing by Subject "P-gp"

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