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Browsing by Subject "Microfluidics"

Now showing items 1-19 of 19

Blister pouches for effective reagent storage and release for low-cost point-of-care diagnostic applications

Author: Smith, S ; Sewart, R ; Land, K ; Roux, P ; Gärtner, C ; Becker, H Date: Feb 2016 Lab-on-a-chip devices are often applied to point-of-care diagnostic solutions as they are low-cost, compact, disposable, and require only small sample volumes. For such devices, various reagents are required for sample preparation and analysis ... Read more
Breaking new boundaries with microfluidics

Author: Land, K ; Mbanjwa, M ; Hugo, S ; Chen, J ; Govindasamy, K Date: 01 Sep 2010 Microfluidics is an important emerging research platform in South Africa. It deals with the control and manipulation of very small quantities of fluids (typically microlitre and smaller) inside micro-channels. Microfluidic-based devices show ... Read more
Contact angle studies on PDMS surfaces fouled by bovine serum albumin

Author: Windvoel, VT ; Mbanjwa, MB ; Land, K Date: 2010 Polydimethylsiloxane (PDMS) has a hydrophobic surface, forming a contact angle of around 110º with deionised water. It is due to its hydrophobic nature that the elastomer is prone to bio-fouling, such as non-specific adsorption of biomaterials ... Read more
Droplet-based microfluidic method for synthesis of microparticles

Author: Mbanjwa, MB ; Windvoel, TV ; Land, KJ Date: Oct 2012 Droplet-based microfluidics has, in recent years, received increased attention as an important tool for performing numerous methods in modern day chemistry and biology, such as synthesis of hydrogel microparticles. The droplet-based ... Read more
Experimental and numerical studies of emulsion formation in a microfluidic T-junction

Author: Mbanjwa, MB ; Land, K ; Jewell, LL ; Gledhill, Irvy MA Date: Jan 2011 The production of water-in-oil (w/o) emulsions in T-junction microfluidic channels was studied through experiments and computational fluid dynamics (CFD). W/o emulsions were produced in the microchannels from deionised water and mineral oil. ... Read more
Fabrication of a multiplexed microfluidic system for scaled up production of cross-linked biocatalytic microspheres

Author: Mbanjwa, M ; Chen, H ; Fourie, L ; Ngwenya, S ; Land, K Date: Jun 2014 Multiplexed or parallelised droplet microfluidic systems allow for increased throughput in the production of emulsions and microparticles, while maintaining a small footprint and utilising minimal ancillary equipment. The current paper ... Read more
Fabrication of paper based microfluidic devices

Author: Govindasamy, K ; Potgieter, S ; Land, K ; Muzenda, E Date: Jul 2012 This paper describes an inexpensive method of fabricating paper based microfluidic devices, a new point of care technology. The method uses a solid ink printer, chromatography paper and a heating source. The printer deposits wax onto the ... Read more
Micro- and nanofluidics for high throughput drug screening

Author: Mathekga, BSP ; Nxumalo, Precious Z ; Thimiri Govindaraj, Deepak B Date: Jan 2022 In this book chapter, we elaborate on the state-of-the-art technology developments in high throughput screening, microfluidics and nanofluidics. This book chapter further elaborated on the application of microfluidics and nanofluidics for ... Read more
Microfluidic cartridges for automated, point-of-care blood cell counting

Author: Smith, Suzanne ; Madzivhandila, Phophi ; Sewart, R ; Govender, Ureshnie ; Becker, H ; Roux, Pieter ; Land, Kevin J Date: Nov 2016 Disposable, low-cost microfluidic cartridges for automated blood cell counting applications are presented in this article. The need for point-of-care medical diagnostic tools is evident, particularly in low-resource and rural settings, and a ... Read more
Microfluidic devices for biological applications

Author: Potgieter, S ; Land, K ; Kotze, L ; Sparrow, R Date: 2010 Microfluidics is a multi-disciplinary field that deals with the behaviour, control and manipulation of fluids constrained to sub-millilitre volumes. It is proving to be a useful tool for biological studies, affording advantages such as reduced ... Read more
Microfluidics as a tool for micro-manipulation

Author: Potgieter, S ; Land, KJ ; Sparrow, RW ; Coetzee, R Date: Oct 2008 Microfluidics is a multi-disciplinary field that deals with the behaviour, control and manipulation of sub-millilitre fluid volumes. It is proving to be a useful tool for biological studies, affording advantages such as reduced cost, faster ... Read more
New microfluidic platform for life sciences in South Africa

Author: Hugo, S ; Land, K Date: Oct 2012 Microfluidic systems provide the ideal platform on which to develop point-of-care (POC) diagnostic devices. A new microfluidic platform, based on centrifugal microfluidic principles, is currently being developed at the CSIR, with the aim ... Read more
Novel mixing method for cross linker introduction into droplet emulsions

Author: Land, KJ ; Mbanjwa, MM ; Korvink, JG Date: Oct 2013 Microfluidic devices are commonly utilised for the manufacture of particles. In certain applications, cross linkers are required to manufacture these particles, and when introduced in continuous form will foul the microfluidic channels. We ... Read more
Novel passive normally closed microfluidic valve

Author: Land, K ; Schneider, F ; Potgieter, S ; Korvink, JG Date: Sep 2009 Microfluidic systems require numerous control valves in order to function properly. These valves form the basic unit of fluid handling within the microfluidic system. Many different valves have been designed and manufactured, both active and ... Read more
Promise of a microfluidic research network in South Africa: establishment of the base with the CSIR

Author: Land, K ; Potgieter, S ; Mbanjwa, M Date: Nov 2008 The CSIR is developing a new technology, broadly referred to as microfluidics, which deals with the behaviour, precise control and manipulation of fluids - with applications in areas such as micro fuel cells, disease detection, chemical and ... Read more
Rapid detection of E. Coli O157:H7 by IFAST and ATP bioluminescence assay for water analysis

Author: Ngamsom, B ; Fourie, L ; Tarn, MD ; Kumar, S ; Moodley, K ; Land, K ; Pamme, N Date: Oct 2016 The present investigation reports isolation and detection of E. coli O157:H7 employing a simple and portable microfluidic device based on immiscible filtration assisted by surface tension (IFAST) and adenosine triphosphate (ATP) bioluminescence ... Read more
Rapid manufacturing for microfluidics

Author: Land, K ; Hugo, S ; Mbanjwa, M ; Fourie, L Date: Oct 2012 Microfluidics refers to the manipulation of very small volumes of fluid. Microfluidics is at the forefront of developing solutions for drug discovery, diagnostics (from glucose tests to malaria and TB testing) and environmental diagnostics ... Read more
Sample to answer visualization pipeline for low-cost point-of-care blood cell counting

Author: Smith, S ; Naidoo, T ; Davies, E ; Fourie, L ; Nxumalo, Z ; Swart, H ; Marais, P ; Land, K ; Roux, P Date: Feb 2015 We present a visualization pipeline from sample to answer for point-of-care blood cell counting applications. Effective and low-cost point-of-care medical diagnostic tests provide developing countries and rural communities with accessible ... Read more
Synthesis of nanomaterials by continuous-flow microfluidics: A review

Author: Makgwane, Peter R ; Ray, Suprakas S Date: Feb 2014 The development of controlled synthesis protocols of nanostructured materials with tailored particle size and shape has been a significant research area in nanoscience and nanotechnology. Much innovative research efforts had been focused on ... Read more

Now showing items 1-19 of 19

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