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Browsing by Subject "Michael addition"

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A one-pot laccase-catalysed synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives, and their anticancer activity

Author: Wellington, Kevin W ; Qwebani-Ogunleye, T ; Kolesnikova, NI ; Brady, D ; De Koning, CB Date: Apr 2013 A commercial laccase, Suberase® from Novozymes, was used to catalyse the synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives. The yields were, in some cases, similar to or better than that obtained by other enzymatic, ... Read more
A one-pot laccase-catalysed synthesis of coumestan derivatives and their anticancer activity

Author: Qwebani-Ogunleye, Tozama ; Kolesnikova, Natalia I ; Steenkamp, Paul A ; De Koning, CB ; Brady, D ; Wellington, Kevin W Date: Dec 2016 Suberase®, a commercial laccase from Novozymes, was used to catalyse the synthesis of coumestans. The yields, in some cases, were similar to or better than that obtained by other enzymatic, chemical or electrochemical syntheses. The compounds ... Read more
Synthesis and characterization of polyamidoamine conjugates of neridronic acid

Author: Aderibigbe, BA ; Sadiku, ER ; Ray, SS ; Mbianda, XY ; Fotsing, MC ; Agwuncha, SC ; Owonubi, SJ Date: Oct 2015 Polyamidoamine conjugates of neridronic acid were synthesized by a one-pot aqueous phase Michael addition reaction of N, N0-methylenebisacrylamide with selected primary and secondary amines and neridronic acid. This reaction involved the use ... Read more

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Browsing by Subject "Michael addition"

Browsing by Subject "Michael addition"

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