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Binding of the mannose-specific lectin, Griffithsin, to HIV-1 gp120 exposes the CD4-binding site

Author: Alexandre, Kabamba B ; Gray, ES ; Pantophlet, R ; Moore, PL ; McMahon, JB ; Chakauya, E ; O'Keefe, BR ; Chikwamba, Rachel K ; Morris, L Date: Sep 2011 The glycans on HIV-1 gp120 play an important role in shielding neutralization-sensitive epitopes from antibody recognition. They also serve as targets for lectins that bind mannose-rich glycans. In this study, the authors investigated the ... Read more

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Browsing by Subject "Mannose-specific lectin"

Browsing by Subject "Mannose-specific lectin"

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