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The role of the C8 proton of ATP in the regulation of phosphoryl transfer within kinases and synthetases

Author: Kenyon, CP ; Steyn, A ; Roth, Robyn L ; Steenkamp, PA ; Nkosi, TC ; Oldfield, LC Date: Jul 2011 Kinase and synthetase enzymes utilise C8D-ATP in preference to non-deuterated ATP. The KIE obtained at low ATP concentrations is clearly a primary KIE demonstrating strong evidence that the bond to the isotopically substituted hydrogen is ... Read more

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Browsing by Subject "Kinases"

Browsing by Subject "Kinases"

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