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The brassinosteroid receptor BRI1 can generate cGMP enabling cGMP-dependent downstream signaling

Author: Wheeler, J ; Wong, A ; Marondedze, C ; Groen, AJ ; Kwezi, Lusisizwe Date: Jun 2017 The brassinosteroid receptor brassinosteroid insensitive 1 (BRI1) is a member of the leucine-rich repeat receptor-like kinase family. The intracellular kinase domain of BRI1 is an active kinase and also encapsulates a guanylate cyclase catalytic ... Read more
Design and synthesis of a heterocyclic compound collection for probing the spatial charactistics of ATP binding sites

Author: Kenyon, CP ; Matlaba, PM ; Parkinson, CJ ; Rousseau, AL ; Van der Westhuyzen, Christiaan W Date: 28 Feb 2006 Recent years have brought about serious interest in the kinases as potential therapeutic targets in a variety of disease conditions. Much of this interest has centred around the preparation and utilisation of species which interact with the ... Read more

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Browsing by Subject "Kinase"

Browsing by Subject "Kinase"

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