Author:Ramalapa, BDate:Oct 2012This presentation show how the formulation of multifunctional polymeric nanoparticles for encapsulation of ATD's with optimum physico-chemical properties has been achieved. Aptamers (against mannose receptors) can assist uptake of nanoparticles ...Read more
Author:Tshweu, L; Katata, L; Naidoo, Saloshnee; Kalombo, Lonji; Swai, HDate:Oct 2012AIDS kills over 1.5 million people a year globally. Current HIV drugs pose many challenges. This presentation shows that nano-encapsulation of HIV drugs achieves controlled and steady drug release, and
reduced dosing frequency.Read more
Author:Meyers, A; Chakauya, E; Shepard, E; Tanzer, FL; Lynch, A; Williamson, A; Rybicki, EPDate:23 Jun 2008Human immunodeficiency virus type 1 (HIV-1) has infected more than 40 million people worldwide, mainly in sub-Saharan Africa. The high prevalence of HIV-1 subtype C in southern Africa necessitates the development of cheap, effective vaccines. ...Read more
Author:Brandt, P; Moodley, D; Pillay, AW; Seebregts, CJ; De Oliveira, TDate:2014The development of drug resistance is a major factor impeding the efficacy of antiretroviral treatment of South Africa’s HIV infected population. While genotype resistance testing is the standard method to determine resistance, access to these ...Read more
Author:Baron, MK; Kinsley, N; Sewell, BT; Jaffer, MA; Capovilla, A; James, W; Khati, MDate:Nov 2008HIV-1 infection and its concomitant disease – Aids, remain major public health problems in southern Africa. While current antiretroviral drugs have prolonged the quality of life for many HIV-positive individuals, they do not eliminate the ...Read more
Author:Maharaj, VDate:Oct 2012In this presentation the author outlines the steps taken in developing a South African indigenous plant-based microbicide to prevent HIV infection in women.Read more
Author:Lotter-Stark, HCT; Rybick, EP; Chikwamba, Rachel KDate:Nov 2012HIV remains a global burden and without an effective vaccine, it is crucial to develop microbicides to halt the initial transmission of the virus. Several microbicides have been researched with various levels of success. Amongst these ...Read more
Author:Manoto, Sello L; Lugongolo, Masixole Y; Govender, Ureshnie; Mthunzi-Kufa, PatienceDate:Mar 2018Human immunodeficiency virus (HIV) is a global health problem. Early diagnosis, rapid antiretroviral therapy (ART) initiation and monitoring of viral load are the key strategies for effective HIV management. Many people in resource limited ...Read more
Author:John, SV; Rotherham, LS; Khati, M; Mamba, BB; Arotiba, OADate:Jul 2014The detection of sequence – specific DNA and HIV glycoprotein 120 (gp120) based on novel generation 4 poly(propylene imine) dendrimer/streptavidin platform is reported. The platform was prepared by the electrodeposition of the dendrimer on a ...Read more