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Antimalarial properties of South African medicinal plants

Author: Pillay, P ; Maharaj, VJ ; Clarkson, C ; Chibale, K Date: Jan 2007 Malaria is the leading cause of death and disease worldwide. The evolution and spread of drug-resistant forms of the causative agent Plasmodium falciparum and the limited number of chemotherapeutic agents available to treat and control the ... Read more
Design, synthesis, and in vitro antituberculosis activity of 2(5H)-Furanone derivatives

Author: Ngwane, AH ; Panayides, Jenny-Lee ; Chouteau, F ; Macingwana, L ; Viljoen, A ; Baker, B ; Madikane, E ; De Kock, C ; Wiesner, L ; Chibale, K ; Parkinson, CJ ; Mmutlane, EM ; Van Helden, P ; Wiid, I Date: Jan 2016 A series of 2(5H)-furanone-based compounds were synthesized from commercially available mucohalic acids. From the first-generation compounds, three showed inhibitory activity (10 µg/mL) of at least 35% against Mycobacterium smegmatis mc(2) ... Read more

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Browsing by Subject "Furanone"

Browsing by Subject "Furanone"

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