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Applying genotoxicology tools to identify environmental stressors in support of river management

Author: Oberholster, Paul J ; Hill, Liesl ; Jappie, S ; Truter, JC ; Botha, A Date: Sep 2015 Although bioassay approaches are useful for identifying chemicals of potential concern, they provide little understanding of the mechanisms of chemical toxicity. Without this understanding, it is difficult to address some of the key challenges ... Read more
Assessment of the effect of nanomaterials on sediment-dwelling invertebrate Chironomustentans larvae

Author: Oberholster, Paul J ; Musee, N ; Botha, A-M ; Botha, PK ; Focke, WW ; Ashton, PJ Date: Mar 2011 Studies were conducted to determine the effects of a panel of seven nanomaterials (NMs), namely: a-alumina, -alumina, precipitated silica; silica fume, calcined silica fume, colloidal antimony pentoxide (Sb2O5), and superfine amorphous ferric ... Read more
Development of a rapid and sensitive battery of bioassays for risk assessment of cyanobacterial microcystin-LR in drinking water of rural water treatment plants, South Africa

Author: Oberholster, Paul J ; Mthethwa, BLS ; Botha, AM Date: Sep 2009 Due to the lack of toxin standards and resource limitations for wide scale use of analytical methods for e.g. high-performance liquid chromatography (HPLC) and enzyme-linked immunosorbent assay (ELISA) in cyanobacterial toxin monitoring, it ... Read more
Evaluation of the probable synergistic toxicity of selected potentiated antiretroviral and antibiotics on some aquatic biomarker organisms

Author: Omotola, EO ; Genthe, B ; Ndlela, Luyanda L ; Olatunji, OS Date: Nov 2023 Environmental effects of active pharmaceutical compounds (APCs) in the environment are not well characterized, hence the need for comprehensive evaluation. This study employed three bioassays using three organisms, namely, Allium cepa, Daphnia ... Read more
Insights into the ecotoxic impact of diclofenac using Daphnia magna as a model organism

Author: Omotola, EO ; Genthe, Bettina ; Ndlela, Luyanda L ; Olatunji, SO Date: Jun 2023 Residues of pharmaceutical compounds (PCs) are among the groups of contaminants of emerging concerns that have been reportedly detected in the aquatic environment. These compounds are widely distributed in diverse water bodies, thus, necessitating ... Read more
Toxicity assessment of reference and natural freshwater sediments with the luminotox assay

Author: Dellamatrice, PM ; Monteiro, RTR ; Blaise, C ; Slabbert, JL ; Gagne, JL ; Alleau, S Date: Aug 2006 We (the authors) examined the possibility of adapting the LuminoTox, a recently-commercialised bioanalytical testing procedure initially developed for aqueous samples, to assess the toxic potential of sediments. A significant correlation was ... Read more

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Browsing by Subject "Bioassays"

Browsing by Subject "Bioassays"

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