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Design and synthesis of a heterocyclic compound collection for probing the spatial charactistics of ATP binding sites

Author: Kenyon, CP ; Matlaba, PM ; Parkinson, CJ ; Rousseau, AL ; Van der Westhuyzen, Christiaan W Date: 28 Feb 2006 Recent years have brought about serious interest in the kinases as potential therapeutic targets in a variety of disease conditions. Much of this interest has centred around the preparation and utilisation of species which interact with the ... Read more
Mechanistic-empirical subgrade design model based on heavy vehicle simulator test results

Author: Theyse, HL ; Hoover, TP ; Harvey, JT ; Monismith, CL ; Coetzee, NF Date: Jun 2006 Although Accelerated Pavement Testing (APT) is often done with specific objectives, valuable pavement performance data is generated over the long-term that may be used to investigate pavement behaviour in general and calibrate mechanistic-empirical ... Read more
Rapid detection of E. Coli O157:H7 by IFAST and ATP bioluminescence assay for water analysis

Author: Ngamsom, B ; Fourie, L ; Tarn, MD ; Kumar, S ; Moodley, K ; Land, K ; Pamme, N Date: Oct 2016 The present investigation reports isolation and detection of E. coli O157:H7 employing a simple and portable microfluidic device based on immiscible filtration assisted by surface tension (IFAST) and adenosine triphosphate (ATP) bioluminescence ... Read more
Studies towards the synthesis of ATP analogs as potential glutamine synthetase inhibitors

Author: Salisu, S ; Kenyon, C ; Kaye, PT Date: May 2011 In research directed at the development of adenine triphosphate (ATP) analogs as potential glutamine synthetase (GS) inhibitors, adenine and allopurinol derivatives have been synthesized either as novel ATP analogs or as scaffolds for the ... Read more

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Browsing by Subject "ATP"

Browsing by Subject "ATP"

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