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Browsing by Impact Area "Array printing & companion Diagn"

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Comparison of the antiviral activity of the microbicide candidate griffithsin and its tandemers derivatives against different modes of HIV-1 transmission

Author: Alexander, Kabamba ; Malatji, Kanyane ; Mulaudzi, Takalani Date: May 2020 Tandemers 2MG, 2MG3, 3MG and 4MG are derivatives of the potent anti-HIV-1 microbicide candidate griffithsin (GRFT). We compared these compounds anti-HIV-1 activity to GRFT using the viruses CAP206.08 and CAAN5342.A2 that have decreased ... Read more
Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications

Author: Singh, Advaita Acarya ; Pooe, O ; Kwezi, Lusisizwe ; Lotter-Stark, T ; Stoychev, Stoyan H ; Alexandra, Kabamba B ; Gerber, Isak B ; Bhiman, JN ; Vorster, J ; Pauly, M ; Zeitlin, L ; Whaley, K ; Mach, L ; Steinkellner, H ; Morris, L ; Tsekoa, Tsepo L ; Chikwamba, Rachel K Date: Apr 2020 Broadly neutralising antibodies (bNAbs) against human immunodeficiency virus type 1 (HIV-1), such as CAP256-VRC26 are being developed for HIV prevention and treatment. These Abs carry a unique but crucial post-translational modification (PTM), ... Read more

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Browsing by Impact Area "Array printing & companion Diagn"

Browsing by Impact Area "Array printing & companion Diagn"

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All of ResearchSpace

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