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Browsing by Author "Van Otterlo, WAL"

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  • Pelly, SC; Parkinson, CJ; Van Otterlo, WAL; De Koning, CB (American Chemical Society, 2005-12-09)
    The metathesis reaction is used as a key step for the synthesis of the indolo [2,3-a] carbazole core of rebeccamycin 13 and the sulfur analog of furostifoline 21. Using the same methodology for the attempted synthesis of ...
  • De Koning, CB; Rousseau, AL; Van Otterlo, WAL (Pergamon-Elsevier Science Ltd, 2003-01-01)
    The importance of naphthalenes and naphthoquinones as bioactive agents and in structural and synthetic chemistry is discussed. How the synthetic chemist gains access to such compounds forms the subject of this review. The ...
  • Panayides, Jenny-Lee; Mathieu, V; Banuls, LMY; Apostolellis, H; Dahan-Farkas, N; Davids, H; Harmse, L; Rey, MEC; Green, IR; Pelly, SC; Kiss, R; Kornienko, A; Van Otterlo, WAL (Elsevier, 2016-06)
    Seventeen silyl- and trityl-modified (5'-O- and 3',5'-di-O-) nucleosides were synthesized with the aim of investigating the in vitro antiproliferative activities of these nucleoside derivatives. A subset of the compounds ...