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Browsing by Author "Rousseau, AL"

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  • Kenyon, CP; Matlaba, PM; Parkinson, CJ; Rousseau, AL; van der Westhuyzen, CW (2006-02-28)
    Recent years have brought about serious interest in the kinases as potential therapeutic targets in a variety of disease conditions. Much of this interest has centred around the preparation and utilisation of species which ...
  • Van der Westhuyzen, CW; Rousseau, AL; Parkinson, CJ (Elsevier Science B.V, 2007)
    In an investigation into the electrophilic nitrosation reactions of a series of 4,6-disubstituted pyrimidine derivatives, a subtle interplay between the electronic nature of the C-4 and C-6 substituents and reactivity was ...
  • De Koning, CB; Rousseau, AL; Van Otterlo, WAL (Pergamon-Elsevier Science Ltd, 2003-01-01)
    The importance of naphthalenes and naphthoquinones as bioactive agents and in structural and synthetic chemistry is discussed. How the synthetic chemist gains access to such compounds forms the subject of this review. The ...
  • Rousseau, AL; Matlaba, P; Parkinson, CJ (Elsevier Science B.V, 2007-06)
    The novel use of zinc chloride to catalyse the one-pot, three component synthesis of imidazo (1,2-a) pyridines for a range of substrates using either conventional heating or microwave radiation is described. This methodology ...
  • Moleele, SS; Gravestock, D; Rousseau, AL; Van Zyl, RL (SACI-GDCh Bi-National Organic Chemistry Conference 2008, 2008-09)
    Malaria causes the death of 2-3 million people annually, most of these children under 5 years of age. Approximately 300 million cases of acute malaria are reported each year, 90% of these in Africa. Until recently, folate ...