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Browsing by Author "Pillay, Priyen"

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Engineering approaches in plant molecular farming for global health

Author: Singh, Advaita A ; Pillay, Priyen ; Tsekoa, Tsepo L Date: Nov 2021 Since the demonstration of the first plant-produced proteins of medical interest, there has been significant growth and interest in the field of plant molecular farming, with plants now being considered a viable production platform for vaccines. ... Read more
A plant-biotechnology approach for producing highly potent anti-HIV antibodies for antiretroviral therapy consideration

Author: Singh, Advaita A ; Pillay, Priyen ; Kwezi, Lusisizwe ; Tsekoa, Tsepo L Date: Dec 2021 Despite a reduction in global HIV prevalence the development of a pipeline of new therapeutics or pre-exposure prophylaxis to control the HIV/AIDS epidemic are of high priority. Antibody-based therapies offer several advantages and have been ... Read more
Recombinant expression, purification and PEGylation of DNA Ligases

Author: Zuma, LK ; Gasa, NL ; Mazibuko, X ; Simelane, BC ; Pillay, Priyen ; Kwezi, Lusisizwe ; Tsekoa, Tsepo L ; Pooe, OJ Date: Apr 2022 Background: Reagent proteins such as DNA ligases play a central role in the global reagents market. DNA ligases are routinely used and are vital in academic and science research environments. Their major functions include sealing nicks by ... Read more
Transient proteolysis reduction of Nicotiana benthamiana-produced CAP256 broadly neutralizing antibodies using CRISPR/Cas9

Author: Singh, Advaita A ; Pillay, Priyen ; Naicker, Previn ; Alexandre, Kabamba B ; Malatji, Kanyane ; Mach, L ; Steinkellner, H ; Vorster, J ; Chikwamba, Rachel K ; Tsekoa, Tsepo L Date: Aug 2022 The hypersensitive response is elicited by Agrobacterium infiltration of Nicotiana benthamiana, including the induction and accumulation of pathogenesis-related proteins, such as proteases. This includes the induction of the expression of ... Read more

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Browsing by Author "Pillay, Priyen"

Browsing by Author "Pillay, Priyen"

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