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Browsing by Author "Moleele, SS"

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  • Bode, ML; Gravestock, D; Moleele, SS; Van der Westhuyzen, CW; Pelly, SC; Steenkamp, PA; Hoppe, HC; Khan, T; Nkabinde, LA (Elsevier, 2011-06)
    During random screening of a small in-house library of compounds, certain substituted imidazo[1,2-a]pyridines were found to be weak allosteric inhibitors of HIV-1 reverse transcriptase (RT). A library of these compounds ...
  • Moleele, SS; Gravestock, D; Rousseau, AL; Van Zyl, RL (SACI-GDCh Bi-National Organic Chemistry Conference 2008, 2008-09)
    Malaria causes the death of 2-3 million people annually, most of these children under 5 years of age. Approximately 300 million cases of acute malaria are reported each year, 90% of these in Africa. Until recently, folate ...