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Browsing by Author "Land, K"

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  • Smith, S; Naidoo, T; Nxumalo, Z; Land, K; Davies, E; Fourie, L; Marais, P; Roux, P (SPIE Digital Library, 2014-03)
    There is an inherent trade-off between cost and operational integrity of microfluidic components, especially when intended for use in point-of-care devices. We present an analysis system developed to characterise microfluidic ...
  • Govindasamy, K; Potgieter, S; Land, K; Muzenda, E (2014-11)
    Paper based sensors have found application in the clinical, environmental, and veterinary monitoring sectors. Popular examples of paper sensors include lateral flow tests (LFTs) and paper based microfluidic devices. The ...
  • Smith, S; Madzivhandila, P; Sewart, R; Govender, Ureshnie; Becker, H; Land, K; Roux, P (2016-10)
    This work presents microfluidic cartridges for automated blood cell counting towards a point-of-care (POC) full blood count (FBC). Total white blood cell count (WBC) and red blood cell count (RBC) tests were implemented ...
  • Smith, S; Sewart, R; Land, K; Roux, P; Gärtner, C; Becker, H (SPIE, 2016-02)
    Lab-on-a-chip devices are often applied to point-of-care diagnostic solutions as they are low-cost, compact, disposable, and require only small sample volumes. For such devices, various reagents are required for sample ...
  • Land, K; Mbanjwa, M; Hugo, S; Chen, J; Govindasamy, K (CSIR, 2010-09-01)
    Microfluidics is an important emerging research platform in South Africa. It deals with the control and manipulation of very small quantities of fluids (typically microlitre and smaller) inside micro-channels. Microfluidic-based ...
  • Smith, S; Mager, D; Perebikovsky, A; Shamloo, E; Kinahan, D; Mishra, D; Delgado, SMT; Kido, H; Saha, S; Ducrée, J; Madou, M; Land, K; Korvink, JG (MDPI, 2016-01)
    We review the utility of centrifugal microfluidic technologies applied to point-of-care diagnosis in extremely under-resourced environments. The various challenges faced in these settings are showcased, using areas in India ...
  • Hugo, S; Land, K; Madou, M; Kido, H (AOSIS Open Journals, 2014-02)
    Microfluidic systems enable precise control over tiny volumes of fluid in a compact and low-cost form, thus providing the ideal platform on which to develop point-of-care diagnostic solutions. Centrifugal microfluidic ...
  • Mbanjwa, MB; Land, K (2008-03)
    The computational fluid dynamics (CFD) simulation results of a capillary-driven flow in a 100 µm serpentine flow-field are presented. A two-dimensional (2D) numerical model based on a conservative level set method (LSM) ...
  • Hugo, S; Land, K; Becker, H (2013-10)
    This paper presents the characterization of microfluidic components for the realization of low-cost point-of-care diagnostic devices, with focus on full blood count applications. Increasing emphasis is being placed on ...
  • Windvoel, VT; Mbanjwa, MB; Land, K (European Cells & Materials Ltd, 2010)
    Polydimethylsiloxane (PDMS) has a hydrophobic surface, forming a contact angle of around 110º with deionised water. It is due to its hydrophobic nature that the elastomer is prone to bio-fouling, such as non-specific ...
  • Khumalo, F; Jordaan, J; Abrahamse, H; Land, K; Potgieter, S; Sparrow, R (South African Institute of Physics (SAIP), 2009-07)
    The development of a micro fluidic circuit for the separation of micro particles is being investigated. There are a wide range of available separation techniques such as acoustic, laminar flow, split flow, optical trapping ...
  • Vilakazi, CB; Roux, P; Land, K (CSIR, 2015-10)
    This presentation will focus on the development and implementation of innovative point-of-care diagnostic devices for low-resource settings. These include technologies such as the Umbiflow diagnostic device, which helps ...
  • Cele, HM; Ojijo, Vincent O; Chen, H; Kumar, S; Land, K; Joubert, T; De Villiers, MFR; Ray, SS (Elsevier, 2014-06)
    This article reports the modification of optical properties of biodegradable/biocompatible polylactide (PLA) using organically modified montmorillonite (OMMT) for microcantilever applications. PLA/OMMT composite films with ...
  • Mbanjwa, MB; Land, K; Jewell, LL; Gledhill, Irvy MA (2011-01)
    The production of water-in-oil (w/o) emulsions in T-junction microfluidic channels was studied through experiments and computational fluid dynamics (CFD). W/o emulsions were produced in the microchannels from deionised ...
  • Mbanjwa, M; Chen, H; Fourie, L; Ngwenya, S; Land, K (SPIE Digital Library, 2014-06)
    Multiplexed or parallelised droplet microfluidic systems allow for increased throughput in the production of emulsions and microparticles, while maintaining a small footprint and utilising minimal ancillary equipment. The ...
  • Govindasamy, K; Potgieter, S; Land, K; Muzenda, E (International Association Of Engineers, 2012-07)
    This paper describes an inexpensive method of fabricating paper based microfluidic devices, a new point of care technology. The method uses a solid ink printer, chromatography paper and a heating source. The printer deposits ...
  • Kruger, J; Smith, S; Land, K; du Plessis, M; Joubert, T-H (RAPDASA 2015, 2015-05)
    This work investigates the properties of conductive circuits inkjet-printed onto the polycarbonate discs used in CD-based centrifugal microfluidics, contributing towards rapidly prototyped electronic systems in smart ...
  • Joubert, T-H; Bezuidenhout, PH; Chen, H; Smith, S; Land, K (Elsevier, 2015-08)
    Inkjet printing is a widely used patterning method in industrial and scientific applications, and has also drawn attention in the field of printed electronics in recent years [1]. In this work, conductive silver tracks ...
  • Hugo, S; Naidoo, T; Swart, H; Potgieter, S; Van Rooyen, P; Land, K (Southern African Institute for Electrical Engineers, 2012-03)
    Optical microscopy is widely accepted as one of the gold standards in disease diagnosis. However, factors such as cost and the need for a trained eye limit the prevalence of such equipment, particularly in resource-limited ...
  • Hugo, S; Naidoo, T; Swart, H; Potgieter, S; Van Rooyen, P; Land, K (SAIEE, 2011-09)
    Microscopy is widely accepted as one of the gold standards in disease diagnosis. However, factors such as cost and the need for a trained eye limit the potential usefulness of such equipment, particularly in resource-limited ...