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Browsing by Author "Hoppe, H"

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  • Bode, M; Gledhill, Irvy MA; Gravestock, D; Hoppe, H; Khan, T; Moleele, S; Nkabinde, L; Pelly, S; van der Westhuyzen, C (CSIR, 2010-09)
    A compound possessing anti-HIV activity similar to that of FDA-approved nevirapine was developed. It acts as a non-nucleoside reverse transcriptase inhibitor, the compound shows good cell permeability, and a quantitative ...
  • Van Brummelen, AC; Becker, JVW; Mancama, Dalubuhle T; Hoppe, H (2010-01)
    In order to establish malaria parasite transfection technology in South Africa, firefly luciferase and green fluorescent protein (GFP) reporter constructs were prepared. In attempt to simplify these constructs, a var intron ...
  • Bode, ML; Gravestock, D; Moleele, S; Van Der Westhuyzen, CW; Hoppe, H; Khan, T; Pelly, SC (2010-01)
    The enzyme reverse transcriptase (RT) is a validated target for the development of anti-HIV drugs. Drugs acting against RT may act at either the catalytic site (NRTIs) or the allosteric site (NNRTIs). During random screening ...
  • Rossouw, C; Chetty, A; Moolman, S; Hoppe, H; Birkholtz, L; Mancama, Dalubuhle T (2010-02)
    Much research remains to be done in order to understand the Plasmodium-liver interaction process. While previous in vitro studies have focused on two-dimensional (2D) cell culture, it is becoming more evident to researchers ...
  • Rossouw, CL; Chetty, A; Moolman, FS; Birkholtz, L-M; Hoppe, H; Mancama, Dalubuhle T (Wiley-Blackwell, 2012-08)
    The thermo-responsive polymer poly(Nisopropylacrylamide) has received widespread attention for its in vitro application in the non-invasive, nondestructive release of adherent cells on two dimensional surfaces. In this ...