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Browsing by Author "Booysen, L"

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  • Semete, B; Booysen, L; Kalombo, Lonji; Ramalapa, B; Hayeshi, R; Swai, HS (Elsevier, 2012-03)
    The surface of nanoparticles is often functionalised with polymeric surfactants, in order to increase systemic circulation time. This has been investigated mainly for intravenously administered nanoparticles. This study ...
  • Booysen, L; Semete-Makokotlela, Boitumelo; Kalombo, Lonji; Swai, H; Kotzé, AF (CSIR, 2010-09-01)
    It has been postulated that antituberculosis drugs encapsulated in polymeric nanoparticles are able to control the release of these drugs in vivo. These biodegradable polymers facilitate sustained/controlled release by ...
  • Semete, B; Booysen, L; Lemmer, Yolandy; Kalombo, Lonji; Katata, L; Verschoor, J; Swai, HS (Elsevier, 2010-10)
    The remarkable physicochemical properties of particles in the nanometer range have been proven to address many challenges in the field of science. However, the possible toxic effects of these particles have raised some ...
  • Semete, B; Kalombo, Lonji; Chelule, P; Benadie, Y; Booysen, L; Katata, L; Naidoo, S; Swai, H (CSIR, 2008-11)
    Current therapeutic management of tuberculosis is inadequate due to non-compliance, lengthy course of treatment and drug- related side effects. In order to address these setbacks, the authors are developing a nanotechnology ...
  • Semete, B; Kalombo, Lonji; Katata, L; Chelule, P; Booysen, L; Lemmer, Yolandy; Naidoo, S; Ramalapa, B; Hayeshi, R; Swai, HS (Taylor & Francis, 2012-03)
    Current treatment of tuberculosis is inadequate due to lengthy treatment course and drug-related toxicity. To address these setbacks, we developed a nanotechnology drug delivery system that can be administered in a single ...
  • Lemmer, Yolandy; Semete, B; Booysen, L; Kalombo, Lonji; Katata, L; Jones, AT; Alexander, C; Khati, M; Swai, HS; Verschoor, JA (2010-06)
    South Africa currently has the highest incidence of TB per 100000 (358 per 100000) people in the world. In 2007 alone 112000 people died of TB in South Africa, of which 94 000 (72%) were co-infected with HIV. Although TB ...