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Browsing by Author "Van Wyngaardt, S"

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Cholesteroid nature of free mycolic acids from m. tuberculosis

Author: Benadie, Y ; Deysel, M ; Siko, DGR ; Roberts, VV ; Van Wyngaardt, S ; Thanyani, ST ; Sekanka, G ; Ten Bokum, AMC ; Collett, LA ; Grooten, J ; Baird, MS ; Verschoor, JA Date: 2008 Mycolic acids (MAs) are a major component of the cell walls of Mycobacterium tuberculosis and related organisms. These alpha-alkyl beta-hydroxy long fatty acids have been the subject of numerous studies for their immunological properties. The ... Read more
Detection of antimycolic acid antibodies by liposomal biosensors

Author: Lemmer, Yolandy ; Thanyani, ST ; Vrey, PJ ; Driver, CHS ; Venter, L ; Van Wyngaardt, S ; Ten Bokum, AMC ; Ozoemena, KI ; Pilcher, LA ; Fernig, DG ; Stoltz, AC ; Swai, HS ; Verschoor, JA Date: 2009 Antibodies to mycolic acid (MA) antigens can be detected as surrogate markers of active tuberculosis (TB) with evanescent field biosensors where the lipid antigens are encapsulated in liposomes. Standard immunoassay such as ELISA, where the ... Read more
Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis

Author: Lemmer, Yolandy ; Kalombo, Lonji ; Pietersen, R-D ; Jones, AT ; Semete-Makokotlela, Boitumelo ; Van Wyngaardt, S ; Ramalapa, BE ; Stoltz, A ; Baker, B ; Verschoor, JA ; Swai, HS ; De Chastellier, C Date: Jun 2015 The appearance of drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challenge to the development of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologies might alleviate the limitations ... Read more

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Browsing by Author "Van Wyngaardt, S"

Browsing by Author "Van Wyngaardt, S"

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