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Browsing by Author "Maharaj, V"

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  • Omolo, JJ; Maharaj, V; Naidoo, D; Malebo, HM; Mtullu, S; Lyaruu, HVM; Koning, CB (American Journal of Research Communication, 2014)
    Phytochemical investigation of the stem and bark of Steganotaenia araliacea led to the isolation of two flavonoids. The structures of these compounds were identified as apigenin 4'-glucoside 1 and sophoraflavone B 2 using ...
  • Van den Berg, N; Mbobela, P; Pillay, P; London, G; Morris, L; Maharaj, V; Khati, M (CSIR, 2011-02)
    A natural compound isolated from extracts of an indigenous plant in the Eastern Cape, South Africa, indicates neutralisation activity against HIV-1 pseudoviruses. This natural compound can potentially be used in a microbicide ...
  • Louvel, S; Moodley, N; Seibert, I; Steenkamp, P; Nthambeleni, R; Vidal, V; Maharaj, V; Klimkait, T (Elsevier, 2013-05)
    As Alepidea amatymbica is commonly used and accepted asmedicinal plant in South Africa for various indications, the scientific basis of its anecdotally described, putative anti-HIV propertieswas investigated. To this aim, ...
  • Van den Berg, N; Mbobela, P; Pillay, P; Maharaj, V; Khati, M (2011-06)
    CSIR Biosciences investigated the anti-HIV properties of a plant indigenous to the Eastern Cape, commonly used by traditional healers. A natural compound isolated from the plant, coded BP36, inhibited infectivity of HIV-1 ...
  • Fouché, Gerda; Nieuwenhuizen, N; Maharaj, V; Van Rooyen, S; Harding, N; Nthambeleni, R; Jayakumar, J; Kirstein, F; Emedi, B; Meoni, P (Elsevier, 2011-01)
    Asthma is a chronic inflammatory disease of the lungs, characterized by increased sensitivity to bronchoconstriction associated with infiltration of immune cells, mucus hypersecretion and structural remodelling of the ...
  • Maharaj, V (2012-10)
    In this presentation the author outlines the steps taken in developing a South African indigenous plant-based microbicide to prevent HIV infection in women.
  • Naidoo, D; Maharaj, V; Crouch, NR; Ngwane, A (Elsevier Publishers, 2010-08)
    The genus Leonotis (Pers.) R.Br. comprises about 10 species, and has been placed within subfamily Lamioideae of the Lamiaceae. Genus members range in habit from tall herbs to small trees. All are native to tropical and/or ...
  • Pillay, V; Mashingaidze, F; Choonara, YE; Du Toit, LC; Buckmann, E; Maharaj, V; Ndesendo, VMK; Kumar, P (Wiley, 2012-06)
    The past decade has seen several effective anti-HIV-1 agent discoveries, yet microbicides continue to disappoint clinically. Our review expounds the view that unsatisfactory microbicide failures may be a result of inefficient ...
  • Maharaj, R; Maharaj, V; Crouch, NR; Bhagwandin, N; Folb, PI; Pillay, P; Gayaram, R (BioMed Central, 2011-08)
    This study was conducted to evaluate whether a selection of South African ethnomedicinal plants included in this study displayed insecticidal properties when screened against adult stages of the mosquito. 381 crude extracts ...
  • Maharaj, R; Maharaj, V; Crouch, NR; Bhagwandin, N; Folb, PI; Pillay, P; Gayaram, R (BioMed Central, 2012-09)
    This study was initiated to establish whether any South African ethnomedicinal plants (indigenous or exotic), that have been reported to be used traditionally to repel or kill mosquitoes, exhibit effective mosquito larvicidal ...
  • Fouché, Gerda; Moodley, N; Maharaj, V (2008-11)
    The bioprospecting group of CSIR Biosciences, focuses on the transformation of African traditional medicines into minimally-processed, scientifically-validated herbal medicines and remedies; the discovery of new pharmaceutical ...