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Browsing by Author "Kolesnikova, NI"

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In vitro anticancer screening of South African plants

Author: Fouché, Gerda ; Cragg, GM ; Pillay, P ; Kolesnikova, NI ; Maharaj, VJ ; Senabe, JV Date: Oct 2008 A total of 7500 plant extracts were screened for in vitro anticancer activity against a panel of three human cell lines (breast MCF7, renal TK10 and melanoma UACC62). Extracts were classified into four categories based on their total growth ... Read more
Investigation of South African plants for anti cancer properties

Author: Khorombi, TE ; Fouché, Gerda ; Kolesnikova, NI ; Maharaj, VJ ; Nthambeleni, R ; Van der Merwe, Martina R Date: 2006 A collaborative research programme between the Council for Scientific and Industrial Research (CSIR) in South Africa and the National Cancer Institute (NCI) in the USA aimed at the screening of plant extracts and identification of potentially ... Read more
A Laccase-catalysed one-pot synthesis of aminonaphthoquinones and their anticancer activity

Author: Wellington, Kevin W ; Kolesnikova, NI Date: May 2012 Nuclear monoamination of a 1,4-naphthohydroquinone with primary aromatic amines was catalysed by the commercial laccase, Novozym 51003, from Novozymes to afford aminonaphthoquinones. The synthesis was accomplished by reacting a mixture of the ... Read more
A one-pot laccase-catalysed synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives, and their anticancer activity

Author: Wellington, Kevin W ; Qwebani-Ogunleye, T ; Kolesnikova, NI ; Brady, D ; De Koning, CB Date: Apr 2013 A commercial laccase, Suberase® from Novozymes, was used to catalyse the synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives. The yields were, in some cases, similar to or better than that obtained by other enzymatic, ... Read more

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Browsing by Author "Kolesnikova, NI"

Browsing by Author "Kolesnikova, NI"

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