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Browsing by Author "Khoza, T"

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Neutralization of several adult and paediatric HIV-1 subtype C isolates using a shortened synthetic derivative of gp120 binding aptamer called UCLA1.

Author: Mufhandu, Hazel T ; Madiga, M ; Gray, E ; Rotherham, L ; Khoza, T ; Morris, L ; Khati, M Date: Jul 2009 This paper present a chemically synthesised derivative of the B40 parental aptamer, called UCLA1 (Cohen et al., 2008), was used for neutralization of endemic subtype C clinical isolates of HIV-1 from adult and paediatric patients and subtype ... Read more
UCLA1, a synthetic derivative of a gp120 RNA aptamer, inhibits entry of human immunodeficiency virus type 1 subtype C

Author: Mufhandu, Hazel T ; Gray, ES ; Madiga, MC ; Tumba, N ; Alexandre, Kabamba B ; Khoza, T ; Wibmer, CK ; Moore, PL ; Morris, L ; Khati, M Date: May 2012 Entry of human immunodeficiency virus type 1 (HIV-1) into cells is mediated by the virion surface envelope (Env) glycoproteins, making it a desirable target for antiretroviral entry inhibitors. We previously isolated a family of gp120 binding ... Read more

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Browsing by Author "Khoza, T"

Browsing by Author "Khoza, T"

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