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Browsing by Author "De Koning, CB"

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  • Pelly, SC; Parkinson, CJ; Van Otterlo, WAL; De Koning, CB (American Chemical Society, 2005-12-09)
    The metathesis reaction is used as a key step for the synthesis of the indolo [2,3-a] carbazole core of rebeccamycin 13 and the sulfur analog of furostifoline 21. Using the same methodology for the attempted synthesis of ...
  • De Koning, CB; Rousseau, AL; Van Otterlo, WAL (Pergamon-Elsevier Science Ltd, 2003-01-01)
    The importance of naphthalenes and naphthoquinones as bioactive agents and in structural and synthetic chemistry is discussed. How the synthetic chemist gains access to such compounds forms the subject of this review. The ...
  • Wellington, Kevin W; Qwebani-Ogunleye, T; Kolesnikova, NI; Brady, D; De Koning, CB (Wiley Online Library, 2013-04)
    A commercial laccase, Suberase® from Novozymes, was used to catalyse the synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives. The yields were, in some cases, similar to or better than that obtained by ...
  • Qwebani-Ogunleye, Tozama; Kolesnikova, Natalia I; Steenkamp, Paul A; De Koning, CB; Brady, D; Wellington, Kevin W (Elsevier, 2016-12)
    Suberase®, a commercial laccase from Novozymes, was used to catalyse the synthesis of coumestans. The yields, in some cases, were similar to or better than that obtained by other enzymatic, chemical or electrochemical ...
  • Zeevaart, JG; Parkinson, CJ; De Koning, CB (Pergamon-Elsevier Science Ltd, 2004-05-24)
    The coupling reaction between ethyl acetoacetate and a number of aryl halides in the presence of palladium acetate, a bulky and electron rich phosphine and K3PO4 is described. The arylated acetoacetate ester is de-acylated ...
  • Zeevaart, JG; Parkinson, CJ; De Koning, CB (Pergamon-Elsevier Science Ltd, 2005-03-07)
    Alpha-Arylation of inethanesulfonamides using palladium catalysis is described. For example, treatment of N-benzyl-Nmethylmethanesulfonamide with catalytic Pd (OAc) (2) in the presence of sodium tert-butoxide, triphenylphosphine ...