Author:Benadie, Y; Semete, B; Venter, L; Kalombo, Lonji; Driver, C; Jones, AT; Swai, H; Verschoor, JADate:Jun 2008The cell wall envelope of Mycobacterium tuberculosis contains unique high molecular weight lipids. Of these, the most abundant are mycolic acids, an extended family of long 2-alkyl 3-hydroxyl fatty acids, typically 70-90 carbon atoms in length, ...Read more
Author:Benadie, Y; Semete, B; Venter, L; Kalombo, Lonji; Driver, C; Jones, AT; Swai, H; Verschoor, JADate:Nov 2008The objective of this project was to explore the encapsulation of mycolic acids into vehicles other than liposomes for delivery into macrophages and addressing the challenges of low solubility. As vehicles nanoparticles (NP) have the advantage ...Read more
