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Browsing by Author "Adams, M"

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Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth. (Lamiaceae)

Author: Mokoka, TA ; Peter, Xolani K ; Fouché, Gerda ; Moodley, N ; Adams, M ; Hamburger, M ; Kaiser, M ; Brun, R ; Maharaj, V ; Koorbanally, Nicoli A Date: Jan 2014 In South Africa, Salvia repens is used traditionally to treat sores, stomach ache and diarrhoea. The high performance liquid chromatography (HPLC)-based activity profiling of S. repens whole plant extract showed an active abietane diterpene, ... Read more
Antiprotozoal Screening of 60 South African plants, and the identification of the Antitrypanosomal Germacranolides Schkuhrin I and II

Author: Mokoka, TA ; Peter, Xolani K ; Zimmermann, S ; Hata, Y ; Adams, M ; Kaiser, M ; Moodley, N ; Maharaj, V ; Koorbanally, Nicoli A ; Hamburger, M ; Brun, B ; Fouché, Gerda Date: Aug 2013 Two hundred and seven extracts were prepared from sixty plants from South Africa and screened for in vitro activity against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum. For the 21 extracts ... Read more
Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products

Author: Zimmermann, S ; Fouché, Gerda ; De Mieri, M ; Yukiko, Y ; Toyonobu ; Nthambeleni, R ; Parkinson, CJ ; Van der Westhuyzen, Christiaan W ; Kaiser, M ; Hamburger, M ; Adams, M Date: Mar 2014 Sesquiterpene lactones (STLs) are natural products that have potent antitrypanosomal activity in vitro and, in the case of cynaropicrin, also reduce parasitemia in the murine model of trypanosomiasis. To explore their structure-antitrypanosomal ... Read more
Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products

Author: Zimmermann, S ; Fouché, Gerda ; De Mieri, M ; Yukiko, Y ; Toyonobu, U ; Nthambeleni, R ; Parkinson, CJ ; Van der Westhuyzen, Christiaan W ; Kaiser, M ; Hamburger, M ; Adams, M Date: Mar 2014 Sesquiterpene lactones (STLs) are natural products that have potent antitrypanosomal activity in vitro and, in the case of cynaropicrin, also reduce parasitemia in the murine model of trypanosomiasis. To explore their structure-antitrypanosomal ... Read more

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Browsing by Author "Adams, M"

Browsing by Author "Adams, M"

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