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Browsing by Author "Lemmer, Yolandy"

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Synthesis, characterization and in vitro cytotoxicity evaluation of polyamidoamine conjugate containing pamidronate and platinum drug

Author: Ndamase, AS ; Aderibigbe, BA ; Sadiku, ER ; Labuschagne, Philip W ; Lemmer, Yolandy ; Ray, Suprakas S ; Nwamadi, M Date: Feb 2018 Bisphosphonates have been found to be effective when combined with anticancer drugs for chemotherapy. In this paper, pamidronate and platinum complexes were conjugated to linear poly(amidoamine)s (PAMAM) to improve the drug efficacy. The ... Read more
Targeted nanodrug delivery systems for the treatment of Tuberculosis

Author: Lemmer, Yolandy ; Semete, B ; Booysen, L ; Kalombo, Lonji ; Katata, L ; Jones, AT ; Alexander, C ; Khati, M ; Swai, HS ; Verschoor, JA Date: Jun 2010 South Africa currently has the highest incidence of TB per 100000 (358 per 100000) people in the world. In 2007 alone 112000 people died of TB in South Africa, of which 94 000 (72%) were co-infected with HIV. Although TB treatments exist, ... Read more
Tuberculosis related drug-lipid interactions demonstrated by evanescent field biosensor

Author: Lemmer, Yolandy ; Siko, G ; Swai, H ; Verschoor, J Date: Aug 2009 This poster is the first demonstration of the use of the evanescent field biosensor to show the interaction between low molecular weight ligate/ligand pairs. The authors demonstrated the interaction of Amphotericin B to either immobilized ... Read more

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Browsing by Author "Lemmer, Yolandy"

Browsing by Author "Lemmer, Yolandy"

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