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Browsing by Author "Birkholtz, L"

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Inhibition of Plasmodium falciparum spermidine synthase indicates unique perturbation-specific effects in the transcriptome and proteome

Author: Becker, J ; Mtwisha, L ; Crampton, BG ; Stoychev, Stoyan H ; Van Brummelen, A ; Louw, A ; Birkholtz, L ; Mancama, Dalubuhle T Date: Mar 2009 Antiplasmodial drug discovery efforts are hampered by the lack of an extensive set of novel, validated drug targets. A requirement of these targets (or the pathways in which they function) is that they prove essential for parasite survival. ... Read more
Optimization of an in vitro system to study the exo-erythrocytic stage of the human malaria parasite, Plasmodium falciparum

Author: Rossouw, C ; Chetty, A ; Moolman, S ; Hoppe, H ; Birkholtz, L ; Mancama, Dalubuhle T Date: Feb 2010 Much research remains to be done in order to understand the Plasmodium-liver interaction process. While previous in vitro studies have focused on two-dimensional (2D) cell culture, it is becoming more evident to researchers that the context ... Read more

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Browsing by Author "Birkholtz, L"

Browsing by Author "Birkholtz, L"

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